Cardoso et al have published recently a study that compared the agreement and prognostic value of the cachexia classification that is mainly derived from the weight loss, with the inflammation based mGPS and have further evaluated the clinical predictors of Cachexia development. The study provides important insights into Cachexia syndrome that affects majority of patients. They have emphasized that mGPS can identify high risk patient subgroup but need not be sued as standalone tool. The study noted that complete evaluation of multiple cachexia domains to identify treatment strategies.